Naked Mole Rats
Something about very cold no snow, snow days in the
south made me think about the info I read up on a while back regarding naked
mole rats. These would be very chilly days for them indeed and
just looking at their nearly hairless images makes me want to turn my crocheted
coffee cup cozies into little naked mole rat sweaters. Naked mole rats are African
underground mammals with 30+ year life spans. Although they are mammals, like
ants or bees, they live in colonies where there is a queen and a few fertile
males and the rest of the naked worker mole rats are sterile. The smaller ones are
tasked with gathering food and maintaining the nest, while larger ones are more
reactive in case of attack. Of particular interest to researchers is that naked
mole rats are resistant to cancer. This is because of an extracellular matrix
in them, the gloop that’s a support for their tissues (like the fat below my
skin) is filled with a substance, high molecular mass hyaluronan (HMM-HA), is
cancer resistant. This hyaluronan acts as a lubricant and helps the naked mole
rat squeeze through tunnels. The rats are so well adapted to living in tight
places that they can almost turn a somersault in their own skin. It is not
known if HMM-HA would lend its cancer protection to humans if human cells were
able to produce it but it may have uses for patients with arthritis some day
through cellular engineering.
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